|
rs12523822
|
|
|
0.710 |
GeneticVariation |
GWASCAT |
Within ethnic group meta-analysis of discovery GWAS and replication set results identified genome-wide significant evidence for association between DKD and rs12523822 on chromosome 6q25.2 in American Indians (P = 5.74x10-9).
|
26305897 |
2015 |
|
rs12523822
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Within ethnic group meta-analysis of discovery GWAS and replication set results identified genome-wide significant evidence for association between DKD and rs12523822 on chromosome 6q25.2 in American Indians (P = 5.74x10-9).
|
26305897 |
2015 |
|
rs14259
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We tested the PSMD9 T2D risk SNPs IVS3+nt460A>G, IVS3+nt437T>C and E197G for linkage to T2D-diabetic nephropathy in 200 Italians T2D families and show linkage to diabetic nephropathy.
|
21439668 |
2011 |
|
rs765798193
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We tested the PSMD9 T2D risk SNPs IVS3+nt460A>G, IVS3+nt437T>C and E197G for linkage to T2D-diabetic nephropathy in 200 Italians T2D families and show linkage to diabetic nephropathy.
|
21439668 |
2011 |
|
rs1799945
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We performed an association study to assess the role of the C282Y and H63D mutations in the HFE gene as a risk factor for type 2 diabetes and diabetic nephropathy.
|
11423500 |
2001 |
|
rs1800562
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We performed an association study to assess the role of the C282Y and H63D mutations in the HFE gene as a risk factor for type 2 diabetes and diabetic nephropathy.
|
11423500 |
2001 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We performed a meta-analysis of 28 association studies focusing on three polymorphisms in the NOS3 gene (G894T (Glu289Asp), 4b/a, and T-786C) and the risk of DN published before July 2009, covering a total of 10,364 subjects.
|
20049477 |
2010 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We observed a significant association of MTHFR C677T with development of diabetic nephropathy in type 2 diabetics.
|
23846111 |
2013 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated the relationship of the ACE insertion/deletion (I/D) and AGT M235T</span> gene polymorphisms in Turkish patients with type 2 diabetes mellitus (DM) with and without diabetic nephropathy.
|
18413162 |
2008 |
|
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated the relationship of the ACE insertion/deletion (I/D) and AGT M235T</span> gene polymorphisms in Turkish patients with type 2 diabetes mellitus (DM) with and without diabetic nephropathy.
|
18413162 |
2008 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated the gender differences in the effect of ACE I/D and AGT M235T polymorphisms on the prognosis of diabetic nephropathy (DN).
|
18849600 |
2009 |
|
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated the gender differences in the effect of ACE I/D and AGT M235T polymorphisms on the prognosis of diabetic nephropathy (DN).
|
18849600 |
2009 |
|
rs3742264
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated the associations of the activity-related variants in the TAFI coding gene (505A/G,1040C/T) with the risk of diabetic nephropathy by examining 297samples including 140 health controls and 157 confirmed diabetic nephropathy patients.
|
22932273 |
2012 |
|
rs12976445
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified miR-125a as a direct regulator of IL-6R, and the genotype of rs12976445 might be a novel predictor of the development of DN in DM.
|
26563755 |
2015 |
|
rs5030718
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We hypothesised that variants rs5030717 and rs5030718 of TLR4 are associated with diabetic nephropathy, hypertension and dyslipidaemia.
|
30211669 |
2018 |
|
rs5030717
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We hypothesised that variants rs5030717 and rs5030718 of TLR4 are associated with diabetic nephropathy, hypertension and dyslipidaemia.
|
30211669 |
2018 |
|
rs745452033
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We have shown previously that the SLC12A3 +78G/A polymorphism in exon 23 (Arg913Gln) was a new candidate for conferring susceptibility to diabetic nephropathy.
|
15915338 |
2005 |
|
rs11643718
|
|
|
0.070 |
GeneticVariation |
BEFREE |
We have shown previously that the SLC12A3 +78G/A polymorphism in exon 23 (Arg913Gln) was a new candidate for conferring susceptibility to diabetic nephropathy.
|
15915338 |
2005 |
|
rs1866813
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We have previously reported genetic association of a single nucleotide polymorphism (SNP), rs1866813, at 3q locus with increased risk of diabetic nephropathy (DN).
|
23441190 |
2013 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We have examined the angiotensin converting enzyme insertion/deletion polymorphism and angiotensinogen methionine 235 threonine polymorphism in a large cohort of Caucasian patients with IDDM and diabetic nephropathy.
|
8877296 |
1996 |
|
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We have examined the angiotensin converting enzyme insertion/deletion polymorphism and angiotensinogen methionine 235 threonine polymorphism in a large cohort of Caucasian patients with IDDM and diabetic nephropathy.
|
8877296 |
1996 |
|
rs56094641
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We further examined the association of rs56094641 with diabetic nephropathy in independent Japanese patients with type 2 diabetes (902 cases and 1,221 controls), and found that the association of this locus with diabetic nephropathy remained significant after integrating all association data (P = 7.62 × 10(-10)).
|
30566433 |
2018 |
|
rs7588550
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We further examined the association of rs7588550 with diabetic nephropathy in an independent Japanese cohort (596 nephropathy cases and 311 controls) and observed the same trend of the association with the initial study.
|
23543049 |
2013 |
|
rs5498
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We found that the ICAM1 K469E(A/G) polymorphism (rs5498) was significantly associated with DN.
|
26255081 |
2016 |
|
rs184003
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We found that the C allele of rs1800625 and the T allele of rs184003 within <i>RAGE</i> gene, interaction between rs1800625 and smoking were all associated with increased DN risk.
|
29228578 |
2017 |